NFL · Week 18
Series since 1999 — 49ers 29, Cardinals 22 · full head-to-head | Season | Round | Result |
| 2026 | Week 3 | ARI 30 @ SF 36 |
| 2025 | Week 11 | SF 41 @ ARI 22 |
| 2025 | Week 3 | ARI 15 @ SF 16 |
| 2024 | Week 18 | SF 24 @ ARI 47 |
| 2024 | Week 5 | ARI 24 @ SF 23 |
| 2023 | Week 15 | SF 45 @ ARI 29 |
| 2023 | Week 4 | ARI 16 @ SF 35 |
| 2022 | Week 18 | ARI 13 @ SF 38 |
Data: nflverse, National Weather Service · About our data